![]() ![]() Specific secondary antibodies are usually used to work in specific laboratory applications. They are available with specificity for whole Ig molecules or antibody fragments such as the Fc or Fab regions. Secondary antibodies may be monoclonal or polyclonal. Secondary antibodies which are marked as probes are useful for the detection, purification or cell sorting applications. Secondary antibodyĪ secondary antibody is an antibody that binds to a primary antibody or antibody fragments. Secondly, compared with rabbit monoclonal antibodies, mouse monoclonal antibodies have lower affinities, and thus have a weak attraction to bind to the target proteins. Firstly, many target proteins are highly conservative between mice and humans, and therefore, those proteins may be recognized as self-antigens by a mouse host, making the antigens less immunogenic than expected. However, researchers have been confronted with a problem of mouse monoclonal antibodies - limitations. It is cost-effective and easy to operate to use a mouse as a host to produce monoclonal antibodies. What are advantages of rabbit monoclonal antibody? Monoclonal antibodies are traditionally produced by hybridoma - myeloma cells fused with the spleen cells, from a mouse which has acquired immunization of the specific antigen. Sino Biological has built up an effective rabbit monoclonal antibody production platform based on our unparalleled expertise in phage display antibody library technology, including the generation of rabbit antibody libraries and selection of high affinity antigen-specific antibodies by phage display. Industry Insights with Yuning Chen on Recombinant Proteins.ExpertAnswers: Yuning Chen on Antibody Production.Universal Vaccine Advancement through AI and Recombinant Technology. ![]() Nanobodies: An Important Tool for the Next Generation of Tumor Diagnostics and Therapeutics.ExpertAnswers: Amy Sheng on Antibody Screening and Discovery.Recombinant DNA Technology and Its Impact on Drug Discovery.CAR-T Cell Therapy Development: From Personalized to off the Shelf Approaches.BioBuzz with Sino | Episode 1: ChatGPT in Biotech.Special Offer: Custom Recombinant Antibody Production Service.Take Our Short Survey to Win Free Gift !.50% OFF: Antibody Humanization Service & AI-Powered Antibody Affinity Maturation Service.Common Cytokine Receptor Signaling Pathway.Beacon ® Single B Cell Screening Service.Recombinant Antibody Production Services. ![]()
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